Janumet 50/1000 mg combines two antihyperglycemic agents with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes.
- Active Ingredients: Sitagliptin (50mg) & Metformin HCl (1000mg)
- Pack Size: 56 Film-coated tablets
- Manufacturer: MSD (Merck Sharp & Dohme)
Janumet targets three key issues in diabetes:
- Sitagliptin: A DPP-4 inhibitor that helps the pancreas release more insulin and decreases glucagon production.
- Metformin: A biguanide that lowers glucose production in the liver and improves insulin sensitivity.
- Administration: Take Janumet twice daily with meals to reduce the risk of stomach upset.
- Consistency: Swallow the tablets whole; do not crush, chew, or break them.
- Professional Advice: Always follow the exact dosage prescribed by your doctor.
- Lactic Acidosis: Rare but serious side effect associated with metformin; avoid excessive alcohol.
- Contraindications: Not for Type 1 diabetes or diabetic ketoacidosis. Avoid use in patients with severe renal impairment.
- Storage: Keep in a dry place at room temperature (below 30°C).



