Diavance 5/500mg is a combination oral anti-diabetic medication used to manage high blood sugar in patients with Type 2 Diabetes. It combines two powerful active ingredients to control glucose in different ways.
- Active Ingredients: Glyburide (5mg) + Metformin HCl (500mg).
- Class: Sulfonylurea and Biguanide combination.
- Primary Goal: To lower blood glucose levels and improve insulin sensitivity.
- Pack Size: 30 Tablets.
Diavance works through a dual-action formula:
- Glyburide: Stimulates your pancreas to produce more natural insulin.
- Metformin: Reduces the amount of sugar produced by the liver and helps the body use its own insulin more effectively.
- Benefit: Better control of HbA1c levels compared to using either medication alone.
Always follow your doctor’s specific instructions. General 2025 guidelines include:
- Administration: Take with meals to reduce the risk of stomach upset.
- Consistency: Do not skip meals while taking this medication to avoid low blood sugar (Hypoglycemia).
- Missed Dose: If you miss a dose, take it with your next meal. If it is almost time for the next dose, skip the missed one.
IMPORTANT: Be aware of the signs of low blood sugar (Hypoglycemia).
- Warning Signs: Sudden sweating, shaking, fast heartbeat, hunger, or blurred vision. Always keep a source of fast-acting sugar (like glucose tablets or fruit juice) nearby.
- Lactic Acidosis: A rare but serious side effect of Metformin. Avoid excessive alcohol consumption while on this medication.
- Kidney Health: Your doctor will monitor your kidney function regularly while you are taking Diavance.
- Nausea, upset stomach, or diarrhea (usually temporary as the body adjusts).
- Metallic taste in the mouth.
- Headache or dizziness.
*If you experience severe abdominal pain or unusual muscle pain, contact your healthcare provider immediately.
- Store at room temperature (below 30°C / 86°F).
- Keep in a dry place away from direct sunlight.
- Keep the container tightly closed and out of reach of children.



