- Major depressive disorder
- Neuropathic pain (nerve pain)
- Prevention of chronic tension-type headaches
- Prevention of migraines
- Prescription Only: This medication is available only with a doctor’s prescription.
- Dosage: The 25mg tablet is a common starting dose, especially for pain and migraine prevention, and is often taken at bedtime due to its sedative properties. Your doctor will determine the appropriate dose and frequency for your specific condition.
- Do not stop suddenly: Do not stop taking Tryptizol without consulting your doctor, as this can cause withdrawal symptoms or worsening of your condition.
- Side Effects: Common side effects can include dry mouth, sleepiness, dizziness, constipation, and weight gain.
- Serious Warnings: Tryptizol carries a boxed warning from the FDA regarding an increased risk of suicidal thoughts and behavior in children, adolescents, and young adults (up to age 24). Patients of all ages should be monitored for unusual changes in mood or behavior, especially when starting the medication or changing doses.
- Interactions: Amitriptyline can interact with many other medications (including MAO inhibitors, certain SSRIs, and alcohol) and medical conditions. It is crucial to inform your doctor about all medications and supplements you are taking



