BONE ONE 1MCG TAB” (also known by brand names like
One-Alpha or Bone-Lift) is an oral tablet containing the active ingredient alfacalcidol. Alfacalcidol is a potent vitamin D analogue used to regulate calcium and phosphate levels in the body, primarily for individuals with conditions affecting vitamin D metabolism, such as kidney disease.
Key Information
- Active Ingredient: Alfacalcidol (1 microgram).
- Purpose: To treat conditions caused by abnormal vitamin D metabolism and low calcium/phosphate levels. It helps strengthen bones, promotes calcium absorption from the intestine, and manages symptoms like bone pain, lesions, and muscle weakness.
- Indications:
- Renal osteodystrophy (bone changes due to kidney failure).
- Hypoparathyroidism and hyperparathyroidism (disorders of the parathyroid glands affecting calcium levels).
- Rickets/osteomalacia (softening or deformity of bones due to lack of calcium).
- Osteoporosis (in some cases).
- Mechanism: Alfacalcidol is rapidly converted by the liver into the active form of vitamin D3 (calcitriol), which then helps balance calcium and phosphate levels.
- Prescription: This medication typically requires a prescription from a healthcare professional.
Important Considerations
- Administration: The administration of this medication is determined by a healthcare provider and is based on the patient’s specific medical condition and laboratory results.
- Monitoring: Regular monitoring of calcium and phosphate levels through blood tests is important while taking this medication. Elevated calcium levels (hypercalcemia) can be a potential side effect.
- Common Side Effects: Some potential side effects include nausea, headache, fatigue, dry mouth, constipation, and muscle or bone pain.
- Contraindications: This medication should not be used by individuals who have high calcium levels in their blood (hypercalcemia) or high vitamin D levels (hypervitaminosis D).
Always adhere to the guidance provided by your healthcare provider or pharmacist when using this medication.
Disclaimer: This information is intended for general knowledge and does not constitute medical advice. Consult with a healthcare professional for diagnosis and treatment.



